In recent years, calls to preserve greater swaths of the Earth's land- and seascapes have grown. In particular, numerous conservationists have called for the protection of half of the planet's surface, a bold initiative that would preserve much of the world's existing biodiversity and ecosystem function. However, the path to such a "half-Earth" preservation model lies largely in uncharted territory, with many potential pitfalls along the way.
Writing in BioScience, Dr. Thomas Campagnaro of the University of Padova, in Italy, and his colleagues elucidate one possible route to better landscape preservation. In their article, the authors describe Natura 2000, the world's largest conservation network. Based in the European Union, the network relies on strong governance, flexible designations, and scientific expertise to produce reliable conservation outcomes.
In this episode of BioScience Talks, Dr. Campagnaro is joined by coauthors Tommaso Sitzia, also of the University of Padova, and Erle Ellis, of the University of Maryland, Baltimore County, to discuss the network and the prospects for scaling it up to a planetary scale.
New tools are making it easier to understand not only our genetic code but also the ways that the code's three-dimensional structure contributes to gene expression. This understanding will be vital in the search for cures to diseases with multiple and complex causes, such as lupus. On this episode of BioScience Talks, we discuss one such tool. It's the product of a collaboration among data scientists, medical scientists, and software engineers, and the new "xapp" allows researchers to view the 3D, looped structure of chromatin and examine the ways in which those loops affect our genes' expression.
Richard Pelikan, a bioinformatician at the Oklahoma Medical Research Foundation, and Austin Schwinn, a data scientist at Exaptive, joined us on this episode to discuss the collaboration, epigenetics, chromatin looping, and the future of understanding human disease. Images discussed in the podcast can be found below the links.