The world faces unprecedented environmental transformation. Successfully managing and adapting to a rapidly changing Earth requires the swift action of well-informed policymakers. In a State of the Science report for BioScience, Audrey Mayer of Michigan Technological University and her colleagues describe a major role for the field of landscape ecology in informing policy and management. She joins us on this episode of BioScience Talks to chat about the article and discuss some practical applications--both those in use now and those on the horizon. Because landscape ecology operates at multiple scales and across human and natural systems, it is a uniquely powerful tool for those who will make tomorrow's environmental and land-use policies.